Speciation genetics: evolving approaches

Nat Rev Genet. 2006 Nov;7(11):851-61. doi: 10.1038/nrg1968. Epub 2006 Oct 3.


Much progress has been made in the past two decades in understanding Darwin's mystery of the origins of species. Applying genomic techniques to the analysis of laboratory crosses and natural populations has helped to determine the genetic basis of barriers to gene flow which create new species. Although new methodologies have not changed the prevailing hypotheses about how species form, they have accelerated the pace of data collection. By facilitating the compilation of case studies, advances in genetic techniques will help to provide answers to the next generation of questions concerning the relative frequency and importance of different processes that cause speciation.

Publication types

  • Historical Article
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Crosses, Genetic
  • Genetic Speciation*
  • Genetic Techniques
  • Genetics / history
  • Genetics / trends
  • Genetics, Population
  • Genomics
  • History, 20th Century
  • History, 21st Century