Frequencies of ABO, MNSs, and Duffy phenotypes among blood donors and malaria patients from four Brazilian Amazon areas

Hum Biol. 2006 Apr;78(2):215-9. doi: 10.1353/hub.2006.0034.


We compared the serological phenotypic frequencies of ABO, MNSs, and Duffy in 417 blood donors and 309 malaria patients from four Brazilian Amazon areas. Our results suggest no correlation between ABO phenotype and malaria infection in all areas studied. We observed significant correlation between the S +s +, S +s -, and S -s + phenotypes and malaria infection in three areas. Some of the Duffy phenotypes showed significant correlation between donors and malaria patients in different areas. These data are an additional contribution to the establishment of differential host susceptibility to malaria.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • ABO Blood-Group System / genetics*
  • Adult
  • Blood Donors
  • Brazil
  • Case-Control Studies
  • Duffy Blood-Group System / genetics*
  • Female
  • Humans
  • MNSs Blood-Group System / genetics*
  • Malaria / blood*
  • Male
  • Phenotype*


  • ABO Blood-Group System
  • Duffy Blood-Group System
  • MNSs Blood-Group System