Isolated sixth nerve palsy secondary to spontaneous intracranial hypotension

Eur J Neurol. 2006 Nov;13(11):1264-5. doi: 10.1111/j.1468-1331.2006.01505.x.


We report the case of a 43-year-old gentleman who presented with an isolated left sixth nerve palsy in association with postural headache. Magnetic resonance imaging showed dural enhancement with downward displacement of the brainstem. This, in association with the signs, symptoms and findings on lumbar puncture, confirmed the diagnosis of spontaneous intracranial hypotension. Treatment was successful with epidural blood patching. The case is discussed and the relevant literature reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abducens Nerve Diseases / etiology*
  • Adult
  • Blood Patch, Epidural
  • Brain Stem / pathology
  • Headache / etiology
  • Humans
  • Intracranial Hypotension / complications*
  • Intracranial Hypotension / diagnosis
  • Intracranial Hypotension / therapy
  • Magnetic Resonance Imaging
  • Male
  • Posture
  • Spinal Puncture