COPI-mediated transport

J Membr Biol. 2006;211(2):65-79. doi: 10.1007/s00232-006-0859-7. Epub 2006 Oct 14.


COPI-coated vesicles are protein and liquid carriers that mediate transport within the early secretory pathway. In this Topical Review, we present their main protein components and discuss current models for cargo sorting. Finally, we describe the striking similarities that exist between the COPI system and the two other characterized types of vesicular carriers: COPII- and clathrin-coated vesicles.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • COP-Coated Vesicles / metabolism*
  • Clathrin-Coated Vesicles / metabolism*
  • Coat Protein Complex I / metabolism
  • Coat Protein Complex I / physiology*
  • Humans
  • Models, Biological
  • Signal Transduction / physiology


  • Coat Protein Complex I