The role of 18F-FDG PET/CT in the evaluation of solid splenic masses

Semin Ultrasound CT MR. 2006 Oct;27(5):420-5. doi: 10.1053/j.sult.2006.06.005.


18F-Fluorodeoxyglucose-positron emission tomography/computed tomography is a noninvasive imaging modality that appears to have a high negative-predictive value for malignancy in assessing solid splenic masses discovered on conventional imaging modalities. Histological sampling is recommended for fluorodeoxyglucose-avid splenic masses, as the main differential diagnosis includes malignancy, either primary or secondary, or granulomatous disease.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Fluorodeoxyglucose F18*
  • Humans
  • Positron-Emission Tomography / methods*
  • Radiopharmaceuticals*
  • Splenic Neoplasms / diagnostic imaging*
  • Tomography, X-Ray Computed / methods*


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18