Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation

Bioinformatics. 2007 Jan 1;23(1):127-8. doi: 10.1093/bioinformatics/btl529. Epub 2006 Oct 18.


Interactive Tree Of Life (iTOL) is a web-based tool for the display, manipulation and annotation of phylogenetic trees. Trees can be interactively pruned and re-rooted. Various types of data such as genome sizes or protein domain repertoires can be mapped onto the tree. Export to several bitmap and vector graphics formats is supported.

Availability: iTOL is available at

MeSH terms

  • Algorithms
  • Animals
  • Chromosome Mapping / instrumentation
  • Chromosome Mapping / methods
  • Computational Biology
  • Data Display*
  • Databases, Genetic*
  • Decision Trees
  • Evolution, Molecular
  • Humans
  • Internet*
  • Phylogeny
  • Software*
  • Species Specificity
  • User-Computer Interface*