Improvement of episodic memory in persons with mild cognitive impairment and healthy older adults: evidence from a cognitive intervention program

Dement Geriatr Cogn Disord. 2006;22(5-6):486-99. doi: 10.1159/000096316. Epub 2006 Oct 16.

Abstract

The efficacy of cognitive training was assessed in persons with mild cognitive impairment (MCI) and persons with normal cognitive aging. Forty-seven participants were included in this study: 28 with MCI and 17 controls. Twenty-one participants received intervention (20 MCI and 9 controls) and 16 participants (8 MCI and 8 controls) received no intervention (waiting-list group). The intervention focused on teaching episodic memory strategies. Three tasks of episodic memory (list recall, face-name association, text memory) were used as primary outcome measures. Results were analyzed using analyses of variance. The intervention effect (pre- and post-intervention difference) was significant on two of the primary outcome measures (delayed list recall and face-name association). A significant pre-post-effect was also found on measures of subjective memory and well-being. There was no improvement in the performance of groups of individuals with MCI and normal elderly persons who did not receive the intervention. These results suggest that persons with MCI can improve their performance on episodic memory when provided with cognitive training.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Attention
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology*
  • Computer-Assisted Instruction
  • Demography
  • Feasibility Studies
  • Female
  • Generalization, Psychological
  • Health Status*
  • Humans
  • Imagination
  • Male
  • Memory Disorders / diagnosis
  • Memory Disorders / epidemiology*
  • Memory Disorders / therapy*
  • Mental Recall
  • Neuropsychological Tests
  • Neuropsychology / methods*
  • Patient Compliance / statistics & numerical data
  • Program Development*
  • Relaxation Therapy
  • Semantics*
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Teaching / methods