Abstract
Balance and cognition were assessed in two patients with uncontrolled complex partial seizures. The patients were on anticonvulsant medications and were treated with left vagal stimulation. Balance and cognition were assessed before and after vagal stimulation, and the results were compared with age matched controls and older patients with Parkinson's disease. Severe impairments of function were found in the epileptic patients, and such negative effects of medication make vagal stimulation a potentially practical alternative treatment for uncontrolled epilepsy.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Carbamazepine / blood
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Carbamazepine / therapeutic use
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Cognition / drug effects
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Cognition / physiology*
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Electric Stimulation Therapy*
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Epilepsy, Temporal Lobe / drug therapy
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Epilepsy, Temporal Lobe / physiopathology*
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Epilepsy, Temporal Lobe / therapy
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Humans
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Male
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Parkinson Disease / physiopathology
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Phenobarbital / blood
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Phenobarbital / therapeutic use
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Phenytoin / blood
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Phenytoin / therapeutic use
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Postural Balance / drug effects
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Postural Balance / physiology*
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Reaction Time
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Time Factors
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Vagus Nerve / physiology*
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Valproic Acid / blood
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Valproic Acid / therapeutic use
Substances
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Carbamazepine
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Valproic Acid
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Phenytoin
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Phenobarbital