Predictors of depression 12 months after cardiac hospitalization: the Identifying Depression as a Comorbid Condition study

Aust N Z J Psychiatry. Nov-Dec 2006;40(11-12):1025-30. doi: 10.1080/j.1440-1614.2006.01927.x.


Objective: To determine characteristics which predict depression at 12 months after cardiac hospitalization, and track the natural history of depression.

Method: Depressive symptoms were monitored at baseline, 3 and 12 months in a cohort of 785 patients, using the self-report Center for Epidemiological Studies Depression Scale. Multinomial regression analyses of baseline clinical and demographic variables identified characteristics associated with depression at 12 months.

Results: Three baseline variables predicted moderate to severe depression at 12 months: depression during index admission, past history of emotional health problems and current smoking. For those who were depressed during cardiac hospitalization, 51% remained depressed at both 3 and 12 months. Persistence was more evident in patients who had moderate to severe depressive symptoms when hospitalized. Mild depression was as likely to persist as to remit.

Conclusions: Three clinically accessible characteristics at the time of cardiac hospitalization can assist in predicting depression at 12 months and may aid treatment decisions. Depressive symptoms persist in a substantial proportion of cardiac patients up to 12 months after hospitalization.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Angina, Unstable / epidemiology
  • Angina, Unstable / psychology
  • Angioplasty, Balloon, Coronary / psychology
  • Angioplasty, Balloon, Coronary / statistics & numerical data
  • Arrhythmias, Cardiac / epidemiology
  • Arrhythmias, Cardiac / psychology
  • Cohort Studies
  • Coronary Artery Bypass / psychology
  • Coronary Artery Bypass / statistics & numerical data
  • Depressive Disorder / diagnosis*
  • Depressive Disorder / psychology
  • Female
  • Follow-Up Studies
  • Heart Diseases / epidemiology
  • Heart Diseases / psychology*
  • Heart Failure / epidemiology
  • Heart Failure / psychology
  • Hospitalization*
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Infarction / epidemiology
  • Myocardial Infarction / psychology
  • Prospective Studies
  • Risk Factors
  • Smoking / epidemiology
  • Smoking / psychology
  • South Australia
  • Statistics as Topic