Toll-like receptor expression and response to specific stimulation in adipocytes and preadipocytes: on the role of fat in inflammation

Ann N Y Acad Sci. 2006 Aug:1072:407-9. doi: 10.1196/annals.1326.021.


Data in this study indicate that both adipocytes and preadipocytes express abroad set of TLRs and they also respond to specific stimulation by cytokine production. The may be of relevance to Crohn's disease and a suggests a closer link between adipose tissue and innate immunity.

MeSH terms

  • Adipocytes / physiology*
  • Adipose Tissue / physiopathology*
  • Animals
  • Humans
  • Immunity, Innate
  • Inflammation / genetics
  • Inflammation / physiopathology*
  • Toll-Like Receptors / genetics
  • Toll-Like Receptors / physiology*


  • Toll-Like Receptors