Fatal attraction: sex, sexually transmitted infections and HIV-1

Int J STD AIDS. 2006 Oct;17(10):643-51. doi: 10.1258/095646206780071018.


The predominant mode of HIV-1 transmission globally is from sexual practices. The risk of HIV-1 transmission by sexual means is a function of infectivity, susceptibility and mode of transmission (type of sexual practice). In addition, transmission may be enhanced by the presence of sexually transmissible infections (STIs). An understanding of the interplay between sexual practices, STIs and HIV-1 may facilitate the development of effective treatment and prevention strategies. These topics are the subject of this review.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Circumcision, Male
  • Disease Transmission, Infectious / prevention & control*
  • Female
  • HIV Infections* / complications
  • HIV Infections* / drug therapy
  • HIV Infections* / prevention & control
  • HIV Infections* / transmission
  • HIV-1*
  • Health Knowledge, Attitudes, Practice
  • Health Surveys
  • Humans
  • Male
  • Risk Factors
  • Sexual Behavior
  • Sexually Transmitted Diseases* / complications
  • Sexually Transmitted Diseases* / drug therapy
  • Sexually Transmitted Diseases* / pathology
  • Ulcer / pathology


  • Anti-Infective Agents