Comparison of serological test kits for diagnosis of typhoid fever in the Philippines

J Clin Microbiol. 2007 Jan;45(1):246-7. doi: 10.1128/JCM.01403-06. Epub 2006 Oct 25.

Abstract

We evaluated four recent antibody-detection kits for typhoid fever by using 177 febrile patients from our hospital, in 75 of whom Salmonella enterica serotype Typhi grew. TUBEX performed best, achieving 94.7% sensitivity and 80.4% specificity. Typhidot, SD Bioline Typhoid, and Mega Salmonella were less specific and, in most cases, less sensitive.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Bacterial / blood*
  • Child
  • Enzyme-Linked Immunosorbent Assay
  • Humans
  • Philippines
  • Reagent Kits, Diagnostic
  • Salmonella typhi / immunology*
  • Sensitivity and Specificity
  • Serologic Tests*
  • Typhoid Fever / diagnosis*
  • Typhoid Fever / microbiology

Substances

  • Antibodies, Bacterial
  • Reagent Kits, Diagnostic