Drug-related problems in patients with angina pectoris, type 2 diabetes and asthma--interviewing patients at home

Pharm World Sci. 2006 Aug;28(4):239-47. doi: 10.1007/s11096-006-9023-9. Epub 2006 Oct 26.


Objective of the study: The objective of the overall study was to create a foundation for improving the quality of counselling practice in pharmacies. The research question addressed in this sub-study was to describe drug-related problems (DRPs) in terms of frequency as well as type in people with angina pectoris, type 2 diabetes and asthma, as the problems were identified through medication reviews and home interviews.

Setting and method: During their pharmacy internships, fourth-year pharmacy students collected data for the study in 1999, 2000 and 2001 by carrying out medication reviews, conducting home interviews and registering DRPs for 414 patients. Data were collected from the following patient groups in the years indicated: in 1999, 123 angina pectoris patients; in 2000, 192 type 2 diabetes patients, and in 2001, 99 asthma patients. The interviews dealt with the patient's drug-related experiences, knowledge, perceptions, problems and actions. The DRPs were registered according to the so-called PI-Doc system.

Results: A medication review was supplemented by qualitative interviews with the three patient groups, which revealed a relatively high number of DRPs compared to other studies. An average of 2.8 DRPs were identified per angina pectoris patient; 4.1 DRPs per type 2 diabetes patient and 4.0 DRPs per asthma patient. "Inappropriate use of medicines by the patient" and "Other problems" (such as limited knowledge of the illness, inappropriate lifestyle, fear of medication, lack of information, etc.) were the two most common DRP sub-categories identified in all three patient groups.

Conclusion: The study provided a profile of a pharmacy-based population of 414 patients visiting the pharmacy, all of whom are at high risk of experiencing drug-related problems. Pharmacy staff needs to take this high rate of DRPs in people with angina pectoris, asthma and type 2 diabetes into account when dispensing medicines to and advising patients from the three groups, especially when explaining how to use medicines appropriately.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angina Pectoris / drug therapy*
  • Asthma / drug therapy*
  • Denmark
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Drug Utilization Review / methods
  • Drug-Related Side Effects and Adverse Reactions*
  • Education, Pharmacy
  • Female
  • House Calls
  • Humans
  • Internship, Nonmedical / methods
  • Interviews as Topic / methods
  • Male
  • Middle Aged
  • Patient Education as Topic / methods
  • Patients / statistics & numerical data
  • Professional Role
  • Students, Pharmacy