The cost utility of strabismus surgery in adults

J AAPOS. 2006 Oct;10(5):394-9. doi: 10.1016/j.jaapos.2006.06.004.


Purpose: Cost-utility analysis evaluates the cost of medical care in relation to the gain in quality-adjusted life years (QALYs). Our purpose was to develop a cost model for surgical care for adult strabismus, to estimate the mean cost per case, to determine the associated gain in QALYs, and to perform cost-utility analysis.

Methods: A cost model incorporated surgery, pre- and postoperative care, and a mean of 1.5 procedures per patient. The gain in QALYs was based on the improvement of utility on a scale from 0 (death) to 1 (perfect health). Utility was measured through physician-conducted interviews employing a time tradeoff question (seeking to estimate the portion of life expectancy a patient would be willing to trade for being rid of disease and associated effects). The interviews were conducted before and 5 to 8 weeks after surgery in 35 strabismic patients (age 19-75 years).

Results: The cost model resulted in an estimated total cost of 4,254 dollars per case. A significant improvement of utility was found: 0.96 +/- 0.11 postoperatively versus 0.85 +/- 0.20 preoperatively (p = 0.00008). Based on the mean life expectancy (36.0 years) of these patients, and discounting outcomes and costs by 3% annually, this resulted in a mean value gain of 2.61 QALYs after surgery and a cost-utility for strabismus surgery of 1,632 dollas/QALY.

Conclusions: In the United States, treatments <50,000 dollars/QALY are generally considered "very cost-effective." Strabismus surgery in adults falls well within this range.

MeSH terms

  • Adult
  • Aged
  • Cost of Illness
  • Cost-Benefit Analysis
  • Female
  • Health Care Costs
  • Health Services Research / economics
  • Humans
  • Male
  • Middle Aged
  • Models, Economic
  • Oculomotor Muscles / surgery*
  • Ophthalmologic Surgical Procedures / economics*
  • Prospective Studies
  • Quality-Adjusted Life Years
  • Strabismus / economics*
  • Strabismus / surgery*
  • United States