Case of childhood granulomatous periorificial dermatitis in a Korean boy treated by oral erythromycin

J Dermatol. 2006 Nov;33(11):806-8. doi: 10.1111/j.1346-8138.2006.00183.x.

Abstract

Childhood granulomatous periorificial dermatitis (CGPD) is a disease presenting most commonly in prepubertal children as yellow-brown papules limited to the perioral, perinasal and periocular regions. The condition is benign, self-limiting and is not associated with systemic involvement. We herein report a case of an 11-year-old Korean boy with multiple, asymptomatic, monomorphic, red-to-yellow-colored papular eruptions on the perioral areas of 7-month duration. Histopathological examination revealed upper dermal and perifollicular granulomatous infiltrate. After using oral erythromycin 500 mg daily for 1 year, the condition resolved completely without leaving a scar.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Dermatitis, Perioral / diagnosis*
  • Dermatitis, Perioral / drug therapy
  • Dermatitis, Perioral / pathology
  • Diagnosis, Differential
  • Erythromycin / administration & dosage
  • Erythromycin / therapeutic use
  • Granulomatosis, Orofacial / diagnosis*
  • Granulomatosis, Orofacial / drug therapy
  • Granulomatosis, Orofacial / pathology
  • Humans
  • Male

Substances

  • Anti-Bacterial Agents
  • Erythromycin