Risk factors for medication misadventure among residents in sheltered housing complexes

Br J Clin Pharmacol. 2007 Feb;63(2):171-6. doi: 10.1111/j.1365-2125.2006.02799.x. Epub 2006 Oct 31.


Aim: To identify risk factors for unplanned hospitalizations among residents of sheltered housing complexes (SHCs).

Methods: Medication-related risk factors for health outcomes among residents of SHCs in Aberdeen (n = 1137) were assessed using a postal questionnaire. Predictors of unplanned hospitalization/emergency department (ED) visit were identified using logistic regression.

Results: Of the 695 (61.1%) responses received, 645 were from residents (mean age 78.2 years) using prescribed medications. One or more risk factors for medication-related problems was seen in 467 (72.4%) respondents; 488 (75.7%) were using medications with high potential for adverse drug reactions (ADRs) in the elderly. Unplanned hospitalizations/ED visits (n = 230) were found to be associated with use of drugs of narrow therapeutic index [P < 0.001; odds ratio (OR) 2.98, 95% confidence interval (CI) 1.69, 5.28]; use of five or more different medications (P = 0.001; OR 2.10, 95% CI 1.34, 3.31); and greater disability (Townsend score) (P = 0.005; OR 1.06, 95% CI 1.02, 1.11).

Conclusion: Residents of SHCs using drugs of narrow therapeutic index, using five or more different medications, and with greater disability warrant periodic monitoring.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adverse Drug Reaction Reporting Systems*
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Behavior
  • Drug Prescriptions
  • Drug-Related Side Effects and Adverse Reactions*
  • Female
  • Hospitalization / trends
  • Housing for the Elderly
  • Humans
  • Male
  • Risk Factors