The anterior visceral endoderm-turning heads

Genesis. 2006 Nov;44(11):565-72. doi: 10.1002/dvg.20249.


The Anterior Visceral Endoderm is an extraembryonic tissue that plays a pivotal role during embryogenesis, being responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate pattering of adjacent embryonic tissue. In this review I discuss the formation and migration of the AVE, and attempt to place some recent findings in the context of a working model.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Body Patterning / physiology*
  • Cell Movement / physiology*
  • Endoderm / cytology*
  • Endoderm / physiology*
  • Extraembryonic Membranes / embryology*
  • Mice
  • Models, Biological*