MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms

Nucleic Acids Res. 2007 Jan;35(Database issue):D515-20. doi: 10.1093/nar/gkl774. Epub 2006 Nov 1.


MACiE (Mechanism, Annotation and Classification in Enzymes) is a database of enzyme reaction mechanisms, and is publicly available as a web-based data resource. This paper presents the first release of a web-based search tool to explore enzyme reaction mechanisms in MACiE. We also present Version 2 of MACiE, which doubles the dataset available (from Version 1). MACiE can be accessed from

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Databases, Protein*
  • Enzymes / chemistry*
  • Enzymes / classification
  • Enzymes / metabolism
  • Internet
  • Protein Conformation
  • Sequence Homology, Amino Acid
  • Software
  • User-Computer Interface


  • Enzymes