Concise synthesis of the (+/-)-Nb-desmethyl-meso-chimonanthine

Candice Menozzi; Peter I Dalko; Janine Cossy

doi:10.1039/b610497e

Concise synthesis of the (+/-)-Nb-desmethyl-meso-chimonanthine

Chem Commun (Camb). 2006 Nov 28:(44):4638-40. doi: 10.1039/b610497e. Epub 2006 Oct 3.

Authors

Candice Menozzi¹, Peter I Dalko, Janine Cossy

Affiliation

¹ Laboratoire de Chimie Organique associé au CNRS, ESPCI, 10 rue Vauquelin, 75231, Paris Cedex 05, France.

PMID: 17082868
DOI: 10.1039/b610497e

Abstract

The first total synthesis of the bis-pyrroloindoline alkaloid (+/-)-Nb-desmethyl-meso-chimonanthine, having a pseudo C2-symmetry, was realised in a seven-step convergent sequence without the use of protecting groups.

MeSH terms

Alkaloids / chemical synthesis*
Alkaloids / chemistry
Indoles / chemical synthesis*
Indoles / chemistry
Molecular Structure
Pyrroles / chemical synthesis*
Pyrroles / chemistry
Stereoisomerism

Substances

Alkaloids
Indoles
N(b)-desmethylchimonathine
Pyrroles