Sculptra: the new three-dimensional filler

Clin Plast Surg. 2006 Oct;33(4):539-50. doi: 10.1016/j.cps.2006.09.001.

Abstract

Sculptra, the synthetic injectable poly-l-lactic acid (PLLA), is a revolutionary three-dimensional filler lasting 18 to 24 months. This unique volumizing agent is best used to globally restore volume to the lower two thirds of the face in patients who have lipoatrophy. Sculptra is a biocompatible, biodegradable, and nonimmunogenic derivative of the alpha-hydroxy-acid family. The size and the slow degradation kinetics of PLLA microparticles act as a stimulus for collagen production, providing lasting volume enhancement in lipoatrophy patients.

MeSH terms

  • Adipose Tissue / pathology
  • Atrophy / drug therapy
  • Atrophy / pathology
  • Cellulose / administration & dosage
  • Cellulose / adverse effects
  • Cellulose / therapeutic use*
  • Face
  • Guidelines as Topic
  • Humans
  • Injections, Subcutaneous
  • Lactic Acid / administration & dosage
  • Lactic Acid / adverse effects
  • Lactic Acid / therapeutic use*
  • Mannitol / administration & dosage
  • Mannitol / adverse effects
  • Mannitol / therapeutic use*
  • Polymers / administration & dosage
  • Polymers / adverse effects
  • Polymers / therapeutic use*
  • Rejuvenation

Substances

  • New-Fill
  • Polymers
  • Lactic Acid
  • Mannitol
  • Cellulose