Botulinum toxin and pregnancy

Skinmed. Nov-Dec 2006;5(6):308. doi: 10.1111/j.1540-9740.2006.05584.x.

Abstract

The overall use of botulinum toxin type A in cosmetic procedures continues to rise, and the incidental exposures of pregnant women to the drug can occur. The author describes 2 patients who received botulinum toxin type A injections during pregnancy. The first patient was a 34-year-old woman who received 54 units of botulinum toxin type A to treat periorbital lines (crow's feet) unaware that she was 6 weeks pregnant. She had a healthy term baby delivered by cesarean section; Apgar scores were 9/10. The second patient was a 37-year-old woman who received 65 units of botulinum toxin type A to treat facial dynamic lines (forehead, glabelar, and periorbital), unaware that she was 5 weeks pregnant. She had a healthy term baby delivered by cesarean section; Apgar scores were 9/10. The 2 patients were injected only once in the first trimester. Both cases did not have any complications or detectable adverse effects on the fetuses.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Botulinum Toxins, Type A / administration & dosage*
  • Botulinum Toxins, Type A / adverse effects
  • Female
  • Humans
  • Injections, Intramuscular
  • Neuromuscular Agents / administration & dosage*
  • Neuromuscular Agents / adverse effects
  • Pregnancy
  • Pregnancy Trimester, First
  • Skin Aging*

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A