Global distribution and reduced penetrance: Lrrk2 R1441C in an Irish Parkinson's disease kindred

Mov Disord. 2007 Jan 15;22(2):291-2. doi: 10.1002/mds.21200.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Arginine / metabolism
  • Binding Sites
  • Disease Progression
  • Glycine / metabolism
  • Histidine / metabolism
  • Humans
  • Ireland
  • Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
  • Male
  • Middle Aged
  • Parkinson Disease / genetics*
  • Parkinson Disease / physiopathology
  • Penetrance*
  • Point Mutation / genetics
  • Protein-Serine-Threonine Kinases / genetics*

Substances

  • Histidine
  • Arginine
  • LRRK2 protein, human
  • Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
  • Protein-Serine-Threonine Kinases
  • Glycine