Antimicrobial effectiveness of a highly concentrated chlorhexidine varnish treatment in teenagers with fixed orthodontic appliances

Angle Orthod. 2006 Nov;76(6):1022-7. doi: 10.2319/070605-218.

Abstract

Objective: To evaluate the recolonization pattern of Mutans streptococci (ms) on densely colonized teeth with fixed orthodontic appliances after treatment with a highly concentrated (36%) chlorhexidine varnish.

Materials and methods: Healthy subjects (n = 19) with fixed orthodontic appliances and high bacterial ms counts in saliva were recruited. In order to establish a baseline registration, plaque adjacent to brackets was sampled and cultivated on Dentocult strips. Following professional tooth cleaning, chlorhexidine varnish was applied on all teeth for 8 minutes. The degree of recolonization with ms was assessed 2 weeks after varnish application in plaque around the brackets. For statistical analysis, the data were subjected to a repeated measures design.

Results: After 2 weeks, ms counts were reduced as compared to baseline values. However, the reduction only weakly met statistical significance (P = .049).

Conclusions: The application of a highly concentrated chlorhexidine varnish in patients with fixed orthodontic appliances does not result in a distinct reduction of ms numbers 2 weeks after treatment.

MeSH terms

  • Adolescent
  • Anti-Infective Agents, Local / pharmacology*
  • Anti-Infective Agents, Local / therapeutic use
  • Chlorhexidine / pharmacology*
  • Chlorhexidine / therapeutic use
  • Colony Count, Microbial
  • Dental Plaque / microbiology*
  • Dental Plaque / prevention & control*
  • Humans
  • Orthodontic Brackets*
  • Saliva / microbiology
  • Statistics, Nonparametric
  • Streptococcus mutans / drug effects*
  • Treatment Failure

Substances

  • Anti-Infective Agents, Local
  • EC40 dental varnish
  • Chlorhexidine