Abstract
In a controlled trial 2 groups of 30 patients presenting various dislipidemic pictures were treated for 50 days with either 3,5-dihydroxy-1,4-bis-(3,4-dihydroxy-cinnamoyloxy)-cyclohexan-carbonic acid-(1) (cynarin, Listrocol) or placebo. Cynarin provied to be able to induce a significant reduction of the hypercholesteremia, the level of pre-beta-lipoproteins, the beta/alpha-lipoprotein ratio and patients' body weight. The administration of cynaria is, therefore, deemed useful in the prophylaxis and therapy of dislipidemic pictures of the arteriosclerotic disease.
Publication types
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Clinical Trial
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Controlled Clinical Trial
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English Abstract
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Randomized Controlled Trial
MeSH terms
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Administration, Oral
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Adolescent
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Adult
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Aged
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Arteriosclerosis / prevention & control
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Body Weight
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Cholesterol / blood
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Cinnamates / administration & dosage
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Cinnamates / pharmacology
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Cinnamates / therapeutic use*
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Clinical Trials as Topic
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Diabetes Mellitus / prevention & control
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Female
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Humans
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Hyperlipidemias / drug therapy*
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Lipoproteins, HDL / blood
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Lipoproteins, LDL / blood
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Male
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Middle Aged
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Time Factors
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Triglycerides / blood
Substances
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Cinnamates
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Lipoproteins, HDL
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Lipoproteins, LDL
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Triglycerides
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Cholesterol