Daytime pulse oximeter measurements do not predict incidence of pain and acute chest syndrome episodes in sickle cell anemia

J Pediatr. 2006 Nov;149(5):707-9. doi: 10.1016/j.jpeds.2006.06.038.

Abstract

A prospective, infant cohort study of children with sickle cell anemia was evaluated to determine the relationship between daytime pulse oximeter measurements and the incidence of pain and acute chest episodes (ACS). A total of 130 children were evaluated. The Pearson correlation between SpO2 and pain and ACS episode rates were 0.00 (P = .97) and 0.10 (P = .27), respectively. Daytime SpO2 cannot independently predict the subsequent rate of pain and ACS episodes.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Acute Disease
  • Adolescent
  • Anemia, Sickle Cell / complications*
  • Anemia, Sickle Cell / physiopathology*
  • Biomarkers / blood
  • Chest Pain / etiology*
  • Chest Pain / physiopathology
  • Child
  • Child, Preschool
  • Circadian Rhythm*
  • Female
  • Follow-Up Studies
  • Hematocrit
  • Hemoglobin, Sickle / metabolism
  • Humans
  • Hypoxia / etiology*
  • Hypoxia / physiopathology
  • Incidence
  • Male
  • Oximetry*
  • Oxygen / analysis
  • Predictive Value of Tests
  • Prospective Studies
  • Risk Factors
  • Syndrome

Substances

  • Biomarkers
  • Hemoglobin, Sickle
  • Oxygen