Central cord injury: pathophysiology, management, and outcomes

Spine J. Nov-Dec 2006;6(6 Suppl):198S-206S. doi: 10.1016/j.spinee.2006.04.006.


Background context: Cervical spinal trauma can result in a heterogeneous collection of spinal cord injury syndromes. Acute traumatic central cord syndrome is a common category of which no uniform consensus on the etiology, pathophysiology, and treatment exists.

Purpose: To evaluate and review potential pathophysiology, current treatment options, and management of central cord injuries.

Study design: Comprehensive literature review and clinical experience.

Methods: A systematic review of Medline for articles related to central cord and spinal cord injury was conducted up to and including journal articles published in September 2005.

Conclusions: Central cord injuries is a clinical definition which is composed of a heterogeneous population for which medical management and surgical decompression and stabilization provide improved neurologic recovery.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Central Cord Syndrome / complications
  • Central Cord Syndrome / physiopathology*
  • Central Cord Syndrome / surgery*
  • Decompression, Surgical
  • Humans
  • Joint Instability / etiology
  • Joint Instability / surgery
  • Prognosis
  • Recovery of Function
  • Spinal Diseases / etiology
  • Spinal Diseases / surgery