Feasibility of short-term outpatient intravenous antibiotic therapy for the management of infectious conditions in pediatric patients

Am J Emerg Med. 2006 Nov;24(7):839-42. doi: 10.1016/j.ajem.2006.03.023.

Abstract

Objective: The objective of this study was to examine the feasibility of short-term outpatient peripheral intravenous (IV) antibiotic therapy for selected emergency department (ED) patients.

Methods: Retrospective analysis of pediatric ED patients presenting with infections of presumed bacterial etiology who received IV ceftriaxone and were discharged with a "capped" IV catheter and instructions to return in 24 hours for reevaluation. Outcome measures included clinical outcome at 24 hours and catheter-related complications.

Results: Twenty-nine patients met study criteria. All returned for reevaluation. In one case, a parent removed the catheter when their child reported "numbness/soreness" at the catheter site. The other 28 patients were judged to be improved, received a second dose of ceftriaxone through the original catheter, and were discharged on oral antibiotic. No adverse events related to the catheter were identified.

Conclusion: Outpatient peripheral IV catheter use appears to be a feasible method for providing serial doses of parenteral antibiotic for the treatment of selected pediatric patients with infectious conditions.

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / administration & dosage*
  • Bacterial Infections / drug therapy*
  • Catheterization, Peripheral
  • Ceftriaxone / administration & dosage*
  • Child
  • Child, Preschool
  • Drug Administration Schedule
  • Emergency Service, Hospital*
  • Feasibility Studies
  • Home Infusion Therapy*
  • Humans
  • Infant
  • Infusions, Intravenous
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Ceftriaxone