Case report of a pituitary macroadenoma treated with artemether

Integr Cancer Ther. 2006 Dec;5(4):391-4. doi: 10.1177/1534735406295311.

Abstract

Introduction: This report describes the case of a male patient with pituitary macroadenoma treated with the artemisinin analog artemether.

Patient and methods: A 75 year-old male patient presented with vision, hearing, and locomotion-related problems. Artemether was administered orally to the patient over a period of 12 months.

Results: Although the tumor remained consistent in size, CT scan shows a reduction in its density, and clinically, the related symptoms and signs resolved significantly as therapy progressed.

Discussion: Overall, the artemether treatment was beneficial in improving the patient's quality of life. Artemether and other artemisinin analogs offer promise for cancer therapy.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / diagnostic imaging
  • Adenoma / drug therapy*
  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Artemether
  • Artemisinins / therapeutic use*
  • Humans
  • Male
  • Pituitary Neoplasms / diagnostic imaging
  • Pituitary Neoplasms / drug therapy*
  • Tomography, X-Ray Computed

Substances

  • Antineoplastic Agents
  • Artemisinins
  • Artemether