Outcomes of commercial renal transplantation: a Canadian experience

Transplantation. 2006 Nov 15;82(9):1130-5. doi: 10.1097/01.tp.0000241072.03400.11.


Background: Financial compensation in exchange for live kidney donation is prohibited in Canada. However, patients in Canada with end-stage renal disease and without a suitable biologically or emotionally related live donor face substantial waiting times on lists for deceased donor kidneys, and so may therefore choose to acquire organs from a live donor in a procedure performed outside Canada as part of a commercial transaction.

Methods: We describe the clinical outcomes in such patients transplanted between 1998 and 2005, managed after their surgery at a single Canadian transplant center.

Results: Patient and graft survival at three years were significantly worse in this group compared to recipients of live biologically related (P<0.0001) and emotionally related transplants (P<0.01) performed in Canada during this period. A number of different surgical and infectious complications were seen, requiring frequent and often lengthy hospitalization.

Conclusion: Patients considering this method of acquiring live-donated kidneys should be counseled of the inherent risks and possible adverse outcomes including diminished dialysis-free survival.

MeSH terms

  • Adult
  • Canada
  • Directed Tissue Donation*
  • Female
  • Graft Rejection / epidemiology
  • Graft Survival
  • Humans
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / economics*
  • Kidney Transplantation / mortality*
  • Living Donors*
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology
  • Risk Factors
  • Treatment Outcome