eSLDB: eukaryotic subcellular localization database

Nucleic Acids Res. 2007 Jan;35(Database issue):D208-12. doi: 10.1093/nar/gkl775. Epub 2006 Nov 15.


Eukaryotic Subcellular Localization DataBase collects the annotations of subcellular localization of eukaryotic proteomes. So far five proteomes have been processed and stored: Homo sapiens, Mus musculus, Caenorhabditis elegans, Saccharomyces cerevisiae and Arabidopsis thaliana. For each sequence, the database lists localization obtained adopting three different approaches: (i) experimentally determined (when available); (ii) homology-based (when possible); and (iii) predicted. The latter is computed with a suite of machine learning based methods, developed in house. All the data are available at our website and can be searched by sequence, by protein code and/or by protein description. Furthermore, a more complex search can be performed combining different search fields and keys. All the data contained in the database can be freely downloaded in flat file format. The database is available at

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arabidopsis Proteins / analysis
  • Caenorhabditis elegans Proteins / analysis
  • Databases, Protein*
  • Eukaryotic Cells / chemistry*
  • Humans
  • Internet
  • Mice
  • Proteome / analysis*
  • Proteome / chemistry
  • Saccharomyces cerevisiae Proteins / analysis
  • Sequence Homology, Amino Acid
  • User-Computer Interface


  • Arabidopsis Proteins
  • Caenorhabditis elegans Proteins
  • Proteome
  • Saccharomyces cerevisiae Proteins