Risk factors for genital and anal warts in a prospective cohort of HIV-negative homosexual men: the HIM study

Sex Transm Dis. 2007 Jul;34(7):488-93. doi: 10.1097/01.olq.0000245960.52668.e5.


Objective: The objective of this study was to determine the prevalence, incidence, and risk factors for genital and anal warts in HIV-negative homosexual men in Sydney.

Study design: The authors conducted a prospective cohort study. Participants were asked whether they had had genital and anal warts at each interview. Details of lifetime sexual contacts and sexual behaviors in the last 6 months were collected.

Results: Among 1,427 men recruited, 8.9% and 19.6% reported a history of genital and anal warts at baseline, respectively. Incidence rates for genital and anal warts were 0.94 and 1.92 per 100 person-years, respectively. In multivariate analysis, both incident genital and anal warts were associated with younger age. In addition, incident genital warts was associated with insertive fingering (P trend = 0.018), whereas incident anal warts was associated with insertive fingering (P trend = 0.007) and insertive fisting (P trend = 0.039).

Conclusions: Anal warts were twice as common as genital warts. Fingering and other manual sexual practices may be an important transmission route for both.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Anus Diseases / epidemiology*
  • Anus Diseases / etiology
  • Anus Diseases / prevention & control
  • Cohort Studies
  • Condylomata Acuminata / epidemiology*
  • Condylomata Acuminata / etiology
  • Condylomata Acuminata / prevention & control
  • HIV Infections*
  • Homosexuality, Male*
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • New South Wales / epidemiology
  • Papillomavirus Infections / epidemiology*
  • Papillomavirus Infections / etiology
  • Papillomavirus Infections / prevention & control
  • Prospective Studies
  • Risk Factors