Small cell neuroendocrine carcinoma of the sinonasal region. A propose of a case

Br J Oral Maxillofac Surg. 2007 Dec;45(8):676-8. doi: 10.1016/j.bjoms.2006.09.014. Epub 2006 Nov 16.


We describe a 70-year-old man with rheumatoid arthritis and pulmonary fibrosis who presented with a month's history of pain in the left lateronasal region and inferior eyelid. On examination there was left exophthalmos, difficulty in coordinating eye movements, inflammation, erythema, and pain. Computed tomography showed a 3 cm mass in the left posterior ethmoid region, a biopsy specimen from which showed a small cell neuroendocrine tumour. He refused operation and was treated unsuccessfully with four cycles of cisplatin and etoposide.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy
  • Carcinoma, Neuroendocrine / diagnosis*
  • Carcinoma, Neuroendocrine / secondary
  • Carcinoma, Small Cell / diagnosis*
  • Carcinoma, Small Cell / secondary
  • Diagnosis, Differential
  • Diplopia / diagnosis
  • Ethmoid Sinus / pathology
  • Exophthalmos / diagnosis
  • Eye Movements
  • Follow-Up Studies
  • Humans
  • Male
  • Maxillary Sinus Neoplasms / diagnosis
  • Nose Neoplasms / diagnosis*
  • Paranasal Sinus Neoplasms / diagnosis*
  • Tomography, X-Ray Computed