Comparative antibacterial activity of polymeric 3-alkylpyridinium salts isolated from the Mediterranean sponge Reniera sarai and their synthetic analogues

Elisabetta Chelossi; Ines Mancini; Kristina Sepcić; Tom Turk; Marco Faimali

doi:10.1016/j.bioeng.2006.09.005

Comparative antibacterial activity of polymeric 3-alkylpyridinium salts isolated from the Mediterranean sponge Reniera sarai and their synthetic analogues

Biomol Eng. 2006 Dec;23(6):317-23. doi: 10.1016/j.bioeng.2006.09.005. Epub 2006 Oct 10.

Authors

Elisabetta Chelossi¹, Ines Mancini, Kristina Sepcić, Tom Turk, Marco Faimali

Affiliation

¹ Institute of Marine Sciences, Section of Marine Technologies, CNR, Via De Marini 6, 16149 Genoa, Italy. chelossi@ge.cnr.it

PMID: 17113346
DOI: 10.1016/j.bioeng.2006.09.005

Abstract

Metabolites from marine sponges are considered a promising alternative to heavy metals in antifouling coatings. Water-soluble polymeric 3-alkylpyridinium salts and 14 related synthetic analogues showed considerable antibacterial activity against marine biofilm bacteria and may represent good candidates as natural biocides for marine technology applications.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anti-Bacterial Agents / chemical synthesis
Anti-Bacterial Agents / isolation & purification*
Anti-Bacterial Agents / pharmacology
Biofilms / drug effects
Porifera / chemistry*
Pyridinium Compounds / chemical synthesis
Pyridinium Compounds / isolation & purification*
Pyridinium Compounds / pharmacology
Water Microbiology*

Substances

Anti-Bacterial Agents
Pyridinium Compounds