Abstract
There is a paucity of comprehensive studies of the APP response in parasitic infection. This should be remedied for two reasons. First, as there is a limited number of cytokines with hepatocyte-stimulating activities, and as each one elicits a unique spectrum of protein changes, examination of the APP response during infection could provide insight into the cytokines involved. Second, the presence of IL-1, IL-6 and TNF, the mediators of the APR, in tissues and circulation have important implications for subsequent immune responses.
MeSH terms
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Acute-Phase Proteins / biosynthesis*
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Acute-Phase Proteins / physiology
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Animals
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Capillary Permeability
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Cytokines / physiology
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Gene Expression Regulation
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Host-Parasite Interactions*
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Humans
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Inflammation
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Liver / metabolism
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Mice
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Nematode Infections / immunology
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Nematode Infections / physiopathology
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Parasitic Diseases / immunology
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Parasitic Diseases / physiopathology*
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Protozoan Infections / immunology
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Protozoan Infections / physiopathology
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Rats
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Schistosomiasis mansoni / immunology
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Schistosomiasis mansoni / physiopathology
Substances
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Acute-Phase Proteins
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Cytokines