Checklist for cognitive and emotional consequences following stroke (CLCE-24): development, usability and quality of the self-report version

Clin Neurol Neurosurg. 2007 Apr;109(3):257-62. doi: 10.1016/j.clineuro.2006.10.002. Epub 2006 Nov 28.


Objective: In this paper a new checklist (CLCE-24) for identification of cognitive and emotional problems after stroke is presented. The CLCE-24 is intended to support a clinical interview by health care professionals other than the trained (neuro)psychologist.

Methods: Patients were interviewed with the CLCE-24, 6 months post stroke. Usability was determined by interviews. Quality of the self-report version was determined using reference instruments (MMSE, CAMCOG).

Results: Sixty-nine patients participated in the study (37 men; mean age 66 years). Both patients and assessors were positive about the use of the CLCE-24. Eighty percent of the patients had cognitive and/or emotional problems (73% cognitive; 51% emotional problems). Patients with complaints on the CLCE-24 also showed problems on the MMSE and the CAMCOG (p<0.05). The CLCE-24 was a predictor of the MMSE and CAMCOG (Adj. R(2)=0.13 and 0.16, respectively) at 12 months post stroke. Internal consistency of the CLCE-24 was good (alpha of 0.81).

Conclusions: The CLCE-24 is a usable and valid instrument for cognitive screening by health care professionals in the stroke service in the chronic phase after stroke.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Aged
  • Cognition Disorders / diagnosis
  • Cognition Disorders / etiology*
  • Expressed Emotion*
  • Female
  • Humans
  • Male
  • Mass Screening / methods*
  • Mood Disorders / diagnosis
  • Mood Disorders / etiology*
  • Neuropsychological Tests
  • Reproducibility of Results
  • Severity of Illness Index
  • Stroke / complications*
  • Stroke / diagnostic imaging
  • Surveys and Questionnaires*
  • Tomography, X-Ray Computed