Antiquitin, a relatively unexplored member in the superfamily of aldehyde dehydrogenases with diversified physiological functions

Cell Mol Life Sci. 2006 Dec;63(24):2881-5. doi: 10.1007/s00018-006-6089-4.


Antiquitin is a member of the aldehyde dehydrogenase superfamily. Sequence analyses indicate that the protein is highly conserved from plants to animals. The plant antiquitins are generally believed to play a role in osmoregulation and/or detoxification. The physiological functions of animal antiquitins remain largely elusive, their involvement in a number of human diseases has been implicated.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aldehyde Dehydrogenase / physiology*
  • Animals
  • Humans
  • L-Aminoadipate-Semialdehyde Dehydrogenase
  • Molecular Sequence Data
  • Plant Proteins / physiology*
  • Proteins / physiology
  • Water-Electrolyte Balance*


  • Plant Proteins
  • Proteins
  • ALDH7A1 protein, human
  • Aldehyde Dehydrogenase
  • Aldh7a1 protein, rat
  • L-Aminoadipate-Semialdehyde Dehydrogenase