Adherens junctions in Drosophila retinal morphogenesis

Trends Cell Biol. 2007 Jan;17(1):26-35. doi: 10.1016/j.tcb.2006.11.006. Epub 2006 Nov 28.

Abstract

Adherens junctions and their core molecular components, classic cadherins, make major contributions to animal morphogenesis. Although the significance of cadherins in development is generally accepted, the mechanisms regulating adherens junction function during morphogenesis remain a subject of intense research. Adherens junctions are involved in the organization of simple cellular patterns, and more complex cell shape changes and cell movements that depend on the dynamic modulation of adherens junctions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Actins / metabolism
  • Adherens Junctions / metabolism*
  • Animals
  • Cadherins / metabolism
  • Catenins / metabolism
  • Cell Adhesion
  • Drosophila
  • Immunoglobulins / chemistry
  • Metamorphosis, Biological
  • Models, Biological
  • Morphogenesis
  • Photoreceptor Cells, Invertebrate / metabolism
  • Pigmentation
  • Retina / growth & development
  • Retina / physiology*

Substances

  • Actins
  • Cadherins
  • Catenins
  • Immunoglobulins