Brassinosteroid signaling: a paradigm for steroid hormone signaling from the cell surface

Science. 2006 Dec 1;314(5804):1410-1. doi: 10.1126/science.1134040.

Abstract

Plants use the coordinated action of several small-molecule hormones to grow and develop optimally in response to a changing environment. Among these hormones are the brassinosteroids (BRs), the polyhydroxylated steroid hormones of plants. BRs bind a small family of leucine-rich repeat receptor kinases at the cell surface, thereby initiating an intracellular signal transduction cascade that results in the altered expression of hundreds of genes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis / growth & development
  • Arabidopsis / metabolism*
  • Arabidopsis Proteins / chemistry
  • Arabidopsis Proteins / metabolism
  • Brassinosteroids
  • Cell Membrane / metabolism*
  • Cholestanols / metabolism*
  • Gene Expression Regulation, Plant
  • Models, Biological
  • Mutation
  • Phosphoprotein Phosphatases / metabolism
  • Phosphorylation
  • Plant Growth Regulators / chemistry
  • Plant Growth Regulators / metabolism*
  • Protein Kinases / chemistry
  • Protein Kinases / metabolism
  • Protein-Serine-Threonine Kinases / metabolism
  • Response Elements
  • Signal Transduction*
  • Steroids / chemistry
  • Steroids / metabolism*
  • Steroids, Heterocyclic / metabolism*
  • Transcription Factors / metabolism

Substances

  • Arabidopsis Proteins
  • BKI1 protein, Arabidopsis
  • Brassinosteroids
  • Cholestanols
  • Plant Growth Regulators
  • Steroids
  • Steroids, Heterocyclic
  • Transcription Factors
  • Protein Kinases
  • BAK1 protein, Arabidopsis
  • BIN2 protein, Arabidopsis
  • BRI1 protein, Arabidopsis
  • Protein-Serine-Threonine Kinases
  • BSU1 protein, Arabidopsis
  • Phosphoprotein Phosphatases
  • brassinolide