Contrast medium extravasation during cerebral angiography for ruptured intracranial aneurysm--clinical analysis of 26 cases

Neurol Med Chir (Tokyo). 1990 Dec;30(13):1011-5. doi: 10.2176/nmc.30.1011.


Since 1976, the authors performed angiography on 837 patients with ruptured intracranial aneurysm, among which extravasation (EV) of contrast medium occurred in 26. Eleven patients underwent radical surgery within 3 hours after the EV, and four recovered well. The other 15 patients were conservatively treated, and all died. A large quantity of EV occurred when consciousness was severely disturbed and angiography was performed within 3 hours of the last attack. Most EV resulted in poor outcome. However, some patients with mildly disturbed consciousness before angiography, even with severe temporary disturbance of consciousness after the EV, recovered well after emergency radical surgery.

MeSH terms

  • Adult
  • Aged
  • Cerebral Angiography / adverse effects*
  • Extravasation of Diagnostic and Therapeutic Materials / etiology*
  • Extravasation of Diagnostic and Therapeutic Materials / surgery
  • Female
  • Humans
  • Intracranial Aneurysm / diagnostic imaging*
  • Male
  • Middle Aged
  • Prognosis
  • Rupture, Spontaneous