[Chemical constituents from roots of Platycodon grandiflorum]
- PMID: 17144467
[Chemical constituents from roots of Platycodon grandiflorum]
Abstract
Objective: To study the chemical constituents from roots of Platycodon grandiflorum.
Method: Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data.
Result: Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8).
Conclusion: Compounds 1,3 and 5 were isolated from this plant for the first time.