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, 68 (11), 1195-8

Neutralizing Antibodies Against Feline Parvoviruses in Nondomestic Felids Inoculated With Commercial Inactivated Polyvalent Vaccines

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Neutralizing Antibodies Against Feline Parvoviruses in Nondomestic Felids Inoculated With Commercial Inactivated Polyvalent Vaccines

Yukiko Sassa et al. J Vet Med Sci.

Abstract

The virus neutralization (VN) antibody titers of serum samples from 18 individuals representing 8 carnivore species vaccinated with commercial polyvalent vaccines optimized for domestic cats containing inactivated feline panleukopenia virus (FPLV) were evaluated against canine parvovirus type 2 (CPV2). In addition, the titers among 5 individuals from 4 carnivore were evaluated against antigenic variants of feline parvoviruses; FPLV, CPV2, CPV2a, CPV2b, CPV2c, mink enteritis virus type 1 (MEV1) and MEV2. The polyvalent vaccines induced cross-reactive VN titers against antigenic variants of feline parvoviruses in nondomestic felids. However, we observed very low cross-reactive VN antibody in lions and Siberian tigers, therefore we should pay attention to CPV infections in these animals even if they were vaccinated with inactivated FPLV vaccines.

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