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Review
. 2006 Oct 15;70(5):98.
doi: 10.5688/aj700598.

Ergot and Its Alkaloids

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Free PMC article
Review

Ergot and Its Alkaloids

Paul L Schiff. Am J Pharm Educ. .
Free PMC article

Abstract

This manuscript reviews the history and pharmacognosy of ergot, and describes the isolation/preparation, chemistry, pharmacodynamics, and pharmacotherapeutics of the major ergot alkaloids and their derivatives. A brief discussion of the hallucinogenic properties of lysergic acid diethylamide is also featured. An abbreviated form of the material found in this paper is presented in a 4-hour didactic format to third-professional year PharmD students as part of their study of vascular migraine headaches, Parkinson's disease, and naturally occurring hallucinogens/hallucinogen derivatives in the modular course offering Neurology/Psychiatry.

Figures

Figure 1
Figure 1
Chemical structures of ergot alkaloids and related important compounds.
Figure 2
Figure 2
Chemical structures of ergot alkaloids and related important compounds.

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