A standardized method to create optic nerve crush: Yasargil aneurysm clip

Exp Eye Res. 2007 Feb;84(2):373-7. doi: 10.1016/j.exer.2006.10.013. Epub 2006 Dec 8.

Abstract

It is often difficult to compare results obtained by different investigators on nerve compression injuries, owing to differences in method of pressure application and noncomparable pressure levels. In the present study, we described a new method to crush the optic nerve by using a specially designed and commercially available device. We think that standardization of the compression methods is necessary to compare interlaboratory results.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Constriction
  • Disease Models, Animal
  • Female
  • Nerve Crush / instrumentation*
  • Optic Nerve / ultrastructure
  • Optic Nerve Injuries / etiology*
  • Optic Nerve Injuries / pathology
  • Rats
  • Rats, Wistar