Prenatal diagnosis of Jarcho-Levin syndrome in the first trimester

Gynecol Obstet Invest. 2007;63(4):200-2. doi: 10.1159/000097845. Epub 2006 Dec 7.

Abstract

Introduction: Jarcho-Levin syndrome is a congenital segmental costo-vertebral deformation with multiple vertebral and numerical or structural rib abnormalities resulting in the 'crab-like' aspect of the chest. We describe an ultrasound antenatal diagnosis of the Jarcho-Levin syndrome with spina bifida during the first trimester of pregnancy.

Case report: Prenatal ultrasonography showed shortened spine with marked kyphoscoliosis and spina bifida.

Conclusion: If a prenatal diagnosis of Jarcho-Levin syndrome is made before viability, the choice of pregnancy termination should be offered to the parents.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Musculoskeletal Abnormalities / complications
  • Musculoskeletal Abnormalities / diagnostic imaging*
  • Pregnancy
  • Pregnancy Trimester, First
  • Spinal Dysraphism / complications
  • Spinal Dysraphism / diagnostic imaging
  • Syndrome
  • Ultrasonography, Prenatal*