Abstract
This article presents an overview of psoriatic arthritis, including the origin, genetic influence and immunologic factors involved in its evolution. The clinical features of psoriatic arthritis are also reviewed in this article, and a discussion of the diagnosis and treatment is included. We have highlighted the current psoriasis treatments, new biological therapies, and their use in practice. This paper reviews the efficacy of these agents, and the importance of their early appliance. The available published data on the efficacy of antimalarials, sulfasalazine, methotrexate, azathioprine and ciclosporin are described, as well as new data on leflunomide and other novel agents.
MeSH terms
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Antibodies, Monoclonal / administration & dosage
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Antibodies, Monoclonal / therapeutic use
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Antirheumatic Agents / administration & dosage
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Antirheumatic Agents / therapeutic use
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Arthritis, Psoriatic* / classification
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Arthritis, Psoriatic* / diagnosis
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Arthritis, Psoriatic* / diagnostic imaging
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Arthritis, Psoriatic* / drug therapy
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Arthritis, Psoriatic* / epidemiology
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Arthritis, Psoriatic* / etiology
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Arthritis, Psoriatic* / immunology
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Biological Products / therapeutic use
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Clinical Trials, Phase II as Topic
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Female
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Glucocorticoids / administration & dosage
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Glucocorticoids / therapeutic use
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Humans
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Male
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Placebos
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Prevalence
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Radiography
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Randomized Controlled Trials as Topic
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Time Factors
Substances
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Antibodies, Monoclonal
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Antirheumatic Agents
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Biological Products
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Glucocorticoids
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Placebos