There is little published experience with the extracorporeal treatment of boric acid overdose, although the pharmacokinetic properties of boric acid suggest a potential role for hemodialysis. We report a rare case of potentially toxic boric acid overdose that was treated successfully with hemodialysis. Based on our experience in this patient and a review of previously reported cases, hemodialysis is effective in decreasing serum boric acid levels and should be considered in the treatment of patients with acute boric acid intoxication.