The role of peritoneal scintigraphy in the detection of continuous ambulatory peritoneal dialysis complications

Ren Fail. 2006;28(8):709-13. doi: 10.1080/08860220600925396.


While continuous ambulatory peritoneal dialysis (CAPD) offers several advantages over hemodialysis in patients with end-stage renal disease, several complications have been recognized. The intraperitoneal instillation of dialysate increases intra-abdominal pressure and consequently predisposes the patient to leaks and herniations through defects in the abdominal wall. The use of an intraperitoneal radiolabeled colloid has been previously described to image entities such as hernias, patent processus vaginalis, abdominal wall, and diaphragmatic leakage. This study shows a simple, non-invasive method of determining the site of dialysate leak and its importance to assist further patient management. There has been a continuing increase in the number of end stage renal disease patients maintained on chronic peritoneal dialysis (CPD). Many patients choose CPD as their preferred chronic dialysis treatment, though approximately 20% of patients who drop out transfer to hemodialysis annually.[1] Although peritonitis remains the major reason for transfer to hemodialysis, other factors such as exit site infections, catheter-related problems, abdominal wall and inguinal hernias, loss of ultrafiltrations, and poor clearance contribute to CPD technique failure.[2] In order to permit the continuation of long-term therapy with CPD, these complications should be resolved. Routine laboratory evaluation or physical examination can detect some CPD-related problems; however, some patients require more complicated investigations to evaluate their problems properly.

MeSH terms

  • Abdominal Wall / diagnostic imaging
  • Abdominal Wall / pathology
  • Adult
  • Aged
  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Genitalia / diagnostic imaging
  • Genitalia / pathology
  • Humans
  • Inguinal Canal / diagnostic imaging
  • Inguinal Canal / pathology
  • Kidney Failure, Chronic / diagnostic imaging*
  • Kidney Failure, Chronic / therapy*
  • Male
  • Middle Aged
  • Peritoneal Cavity / diagnostic imaging
  • Peritoneal Cavity / pathology
  • Peritoneal Dialysis, Continuous Ambulatory / adverse effects*
  • Pleural Effusion / diagnostic imaging
  • Pleural Effusion / etiology
  • Predictive Value of Tests
  • Radionuclide Imaging
  • Research Design
  • Treatment Failure