Identification of novel Sinorhizobium meliloti mutants compromised for oxidative stress protection and symbiosis

J Bacteriol. 2007 Mar;189(5):2110-3. doi: 10.1128/JB.01802-06. Epub 2006 Dec 15.

Abstract

Employing a novel two-part screen, we identified Sinorhizobium meliloti mutants that were both sensitive to hydrogen peroxide and symbiotically defective on the host plant Medicago sativa. The mutations affect a wide variety of cellular processes and represent both novel and previously identified genes important in symbiosis.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cytochromes c / biosynthesis
  • Hydrogen Peroxide / pharmacology
  • Mutation
  • Oxidative Stress*
  • Polysaccharides, Bacterial / biosynthesis
  • Protein Biosynthesis
  • Sinorhizobium meliloti / metabolism*
  • Symbiosis*

Substances

  • Polysaccharides, Bacterial
  • succinoglycan
  • Cytochromes c
  • Hydrogen Peroxide