Essentials of local anesthetic pharmacology

Anesth Prog. Fall 2006;53(3):98-108; quiz 109-10. doi: 10.2344/0003-3006(2006)53[98:EOLAP]2.0.CO;2.

Abstract

It is impossible to provide effective dental care without the use of local anesthetics. This drug class has an impressive history of safety and efficacy, but all local anesthetics have the potential to produce significant toxicity if used carelessly. The purpose of this review is to update the practitioner on issues regarding the basic pharmacology and clinical use of local anesthetic formulations.

MeSH terms

  • Anesthetics, Local / administration & dosage
  • Anesthetics, Local / adverse effects
  • Anesthetics, Local / chemistry
  • Anesthetics, Local / pharmacology*
  • Carticaine / pharmacology
  • Drug Hypersensitivity
  • Humans
  • Procaine / pharmacology
  • Vasoconstrictor Agents / pharmacology

Substances

  • Anesthetics, Local
  • Vasoconstrictor Agents
  • Procaine
  • Carticaine