Chikungunya outbreaks caused by African genotype, India

Prasanna N Yergolkar; Babasaheb V Tandale; Vidya A Arankalle; Padmakar S Sathe; A B Sudeep; Swati S Gandhe; Mangesh D Gokhle; George P Jacob; Supriya L Hundekar; Akhilesh C Mishra

doi:10.3201/eid1210.060529

Chikungunya outbreaks caused by African genotype, India

Emerg Infect Dis. 2006 Oct;12(10):1580-3. doi: 10.3201/eid1210.060529.

Authors

Prasanna N Yergolkar¹, Babasaheb V Tandale, Vidya A Arankalle, Padmakar S Sathe, A B Sudeep, Swati S Gandhe, Mangesh D Gokhle, George P Jacob, Supriya L Hundekar, Akhilesh C Mishra

Affiliation

¹ National Institute of Virology, Pune, India.

Abstract

Chikungunya fever is reported in India after 32 years. Immunoglobulin M antibodies and virus isolation confirmed the cause. Phylogenic analysis based on partial sequences of NS4 and E1 genes showed that all earlier isolates (1963-1973) were Asian genotype, whereas the current and Yawat (2000) isolates were African genotype.

MeSH terms

Aedes / virology
Alphavirus Infections / epidemiology*
Alphavirus Infections / virology*
Animals
Chikungunya virus / genetics*
Chikungunya virus / isolation & purification
Disease Outbreaks*
Female
Genotype
Humans
India / epidemiology
Insect Vectors / virology
Male
Phylogeny
Reverse Transcriptase Polymerase Chain Reaction / methods